Single-molecule Force Studies
Wesley P. Wong, P.I.
The widespread use of single-molecule manipulation techniques has been impeded by the slow and difficult nature of making measurements one-molecule-at-a-time, and the often high cost of the necessary equipment. We have developed a new approach to meet these challenge that we call single-molecule centrifugation. Our first paper on this method has just been published as a letter in Biophysical Journal.
New publication: single-molecule centrifugation
6/2/10
Our new approach for performing massively parallel single-molecule force measurements using centrifugal force has just been published. This paper introduces an instrument that we call the Centrifuge Force Microscope.
photo credit: John Chervinsky
This work has been feature in Nature as a Research Highlight. News of this work has also been reported by a variety of sites including Science Daily, Softpedia News, and Physorg.
To learn more about this approach, visit our research page, or read the publication.